Confirmed: The 2023 Montagna Symposium on the Biology of Skin will be hosted in-person.

 

 

Program subject to change

2023:

Visualizing the Future of Skin Biology and Dermatology

The 70th anniversary Montagna Symposium on the Biology of Skin, chaired by Dr. Dennis Roop, will take a broad look into the future of skin biology and Dermatology and include sessions on Skin Cancers, Tissue Repair and Fibrosis, Skin Inflammation and Keratinocyte – Immune Cell Cross-talk, and Emerging Therapeutic Approaches. Joe Gray, Ph.D. (OHSU) will provide the keynote speech.

Program Chair and Symposium Co-director
Dennis Roop, Ph.D.

Symposium Co-director
Sancy Leachman, M.D., Ph.D.

Symposium Co-organizers
Stuart Yuspa, M.D.
Thomas Krieg, M.D., Ph.D.
Sabine Werner, Ph.D.

Session 1: Skin Cancer; Chair: Stuart Yuspa, M.D. (NIH)
Session 2: Tissue Repair and Fibrosis; Chair: Thomas Krieg, M.D., Ph.D. (Cologne)
Session 3: Keratinocyte – Immune Cell Cross-talk in Skin Inflammation; Chair: Sabine Werner, Ph.D. (ETH Zurich)
Session 4: Emerging Diagnostic and Therapeutic Approaches; Chairs: Dennis Roop, Ph.D. (Colorado), Sancy Leachman, M.D., Ph.D. (OHSU)

 

Thursday, Oct 19
2:00 p.m. – 4:00 p.m.Shuttle Bus from PDX Leaves (reservation required)
4:00 p.m. – 7:00 p.m.Arrival and Check-in
6:00 p.m. – 7:00 p.m.Welcome Reception and introductory comments

Sancy Leachman, M.D., Ph.D. (Oregon Health & Science University) and Dennis Roop, Ph.D. (Colorado)

7:15 p.m. – 8:15 p.m.Keynote: Joe Gray, Ph.D. (OHSU)

“Imaging, Electron microscopy”

 

Friday, Oct 20
7:00 a.m. – 8:00 a.m.Breakfast
8:00 a.m. – 8:15 a.m.Introductory Remarks

Dennis Roop (Colorado) and Sancy Leachman, M.D. Ph.D. (Oregon Health and Science University)

8:15 a.m. – 8:25 a.m.Session 1: Advances in skin cancer research and therapy

Session Moderator: Stuart Yuspa (NIH)

8:25 a.m. – 8:55 a.m.TBD

“Fibroblast subpopulations in cancer stroma with distinct functional properties to enhance or resist cancer progression.”

8:55 a.m. – 9:05 a.m.Discussion
9:05 a.m. – 9:35 a.m.Allan Balmain (UCSF)

“Squamous cancer, pre-cancer, insights on tumor promotion.”

9:35 a.m. – 9:45 a.m.Discussion
9:45 a.m. – 10:10 a.m.Andrzej Dlugosz (Michigan)

“Genetics, pathobiology and potential therapy of the highly metastatic Merkel Cell cancers.”

10:10 a.m. – 10:20 a.m.Discussion/Coffee Break
10:20 a.m. – 10:50 a.m.Sergey Nikolaev (Gustave Roussey, Paris)

 “Basal Cell Carcinoma (Treatment Resistance, Its Mechanism & Current Clinical Trials to Overcome It)

10:50 a.m. – 11:00 a.m.Discussion
11:00 a.m. – 11:30 a.m.Brigitte Widemann (NIH)

“Current understanding of Neurofibromatosis pathogenesis and treatment”

11:30 a.m. – 11:40 a.m.Discussion
11:40 a.m. – 12:10 p.mStephanie Goff (NIH)

“Cell-based immunotherapy for melanoma”

12:10 p.m. – 12:20 p.m.Discussion
12 noon – 1:15 p.m.Lunch
12:30 p.m. – 1:15 p.m.TBD
1:15 p.m. – 1:20 p.m.Session 2: Tissue Repair and Fibrosis
Session Moderator: Thomas Krieg (Cologne)
1:20 p.m. – 1:45 p.m.Thomas Krieg (Cologne)

“Regulation of Fibroblast Activities – Implications for Tissue Repair and Fibrosis”

1:45 p.m. – 1:50 p.m.Discussion
1:50 p.m. – 2:15 p.m.Maksim Plikus (UC)

“Cell – Cell Communication in Skin Wound Healing (Tentative)”

2:15 p.m. – 2:25 p.m.Discussion
2:25 p.m. – 2:50 p.m.Michael Longaker (Stanford)

“Fibroblasts subsets, and the identification of specific signatures and their involvement in scar formation.”

2:50 p.m. – 3:00 p.m.Discussion
3:00 p.m. – 3:15 p.m.Coffee Break
3:15 p.m. – 3:40 p.m.Sabine Eming (Cologne)

“Macrophage subsets and the role of reparative macrophages in remodeling the extracellular matrix “

3:40 p.m. – 3:50 p.m.Discussion
3:50 p.m. – 4:15 p.m.TBD

“New Therapeutics in Scleroderma: Senolytics and Mechanotherapeutics”

4:15 p.m. – 4.25 p.m.Discussion
 

4:25 p.m. – 4:50 p.m.

 

Xiao-Jing Wang (UC Davis)

“A novel approach for treating radiation induced oral mucositis using a Smad7-based tat protein”

4:50 p.m. – 5:00 p.m.Discussion
5:00 p.m. – 5:15 p.m.Awards Presentation

·         Society of Investigative Dermatology Eugene M. Farber Travel Awards for Young Investigators

·         Japanese Society for Investigative Dermatology Travel Award

·         Korean Society for Investigative Dermatology Travel Award

Director’s Award for Diversity

5:15 p.m. – 7:00 p.m.Poster Reception

(Heavy appetizers served.)

7:00 p.m. – 8:00 p.m.Optional Activity – TBD
8:00pmTBD

Saturday, Oct 21
7:00 a.m. – 7:55 a.m.Breakfast
8:00 a.m. – 8:05 a.m.Announcements
8:05 a.m. – 8:15 a.m.Session 3: Keratinocyte – Immune Cell Cross-talk in Skin Inflammation

Session Moderator: Sabine Werner (ETH, Zurich)

8:15 a.m. – 8:45 a.m.Sabine Werner (ETH, Zurich)
8:45 a.m. – 8:55 a.m.Discussion
8:55 a.m. – 9:25 a.m.Sara Brown (Edinburgh)

“Keratinocytes are immunologically-active cells in their own right: evidence from genetic studies and primary cell culture”

9:25 a.m. – 9:35 a.m.Discussion
9:35 a.m. – 10:05 a.m.Michel Gilliet (Lausanne) 

“Reciprocal immune-keratinocyte interactions in the pathogenesis of psoriasis”

 

10:05 a.m. – 10:15 a.m.Discussion
10:15 a.m. – 10:35 a.m.Break
10:35 a.m. – 11:05 a.m.Shruti Naik (NYU)

“Targeting immune-epithelial circuits in inflammatory skin disease”

11:05 a.m. – 11:15 a.m.Discussion
11:15 a.m. – 11:30 a.m.Short Talk Chosen from Submitted Abstracts (tentative)
11:30 a.m. – 11:45 a.m.Short Talk Chosen from Submitted Abstracts (tentative)
11:45 a.m.Lunch
1:30 p.m. – 4:45 p.m.FREE TIME / GOLF / CASCADE HIKE
 
4:45 p.m. – 5:50pmMentorship Mixer (Long House) OR Facilitated workshop
6 p.m. – 7:15 p.m.Dinner 
7:15 p.m. – 8:15 p.m.Keynote –TBD

 

Sunday, Oct 22
7:00 a.m. – 7:55 a.m.Breakfast
8:00 a.m. – 8:05 a.m.Announcements
8:05 a.m. – 8:15 a.m.Session 4: Emerging Diagnostic and Therapeutic Approaches

Session Moderator: Dennis Roop (Colorado)

8:15 a.m. – 8:45 a.m.Tony Oro (Stanford)

“FDA approval for clinical trials delivering keratinocytes derived from genetically corrected iPSCs to RDEB patients”

 

8:45 a.m. – 8:55 a.m.Discussion
8:55 a.m. – 9:25 a.m.Ganna Bilousova (Colorado)

FDA approval for clinical trials delivering keratinocytes derived from genetically corrected iPSCs to RDEB patients”

 

9:25 a.m. – 9:35 a.m.Discussion
9:35 a.m. – 10:05 a.m.Peter Marinkovich (Stanford)

 

 “RDEB which utilizes the topical application of herpes simplex viral vectors containing the coding sequence for Collagen VII”

10:05 a.m. – 10:15 a.m.Discussion
10:15 a.m. – 10:35 a.m.Break
10:35 a.m. – 11:00 a.m.Luis Garza (Johns Hopkins) “Results of an ongoing clinical trial attempting to reprogram (thicken) the epidermal layer at the stump site in people with below the knee amputations by injecting autologous volar fibroblasts (isolated from the palm or sole).”

 

11:00- 11:15Discussion
11:15-11:40Christoph Ellebrecht (Upenn), “Results of a clinical trial with Aimee Payne of a chimeric antigen receptor (CAR) T cell therapy for mucosal pemphigus vulgaris”
11:40 – 11:55Discussion
11:55 a.m. – 1:00 p.m.Lunch
1:00 p.m. – 1:15p.m.TBD
1:15 p.m. – 2:00 p.m.TBD
2 p.m. – 2:15 p.m.Discussion
2:15 p.m. – 2:40 p.m.David Huang (OHSU)  “Talk Title TBD” Imaging
2:40pm – 2:55Discussion
2:55 pm -3:20pmTBD
3:20 p.m. – 3:30 p.m.Discussion
3:30 p.m. – 3:45 p.m.Break
3:45 p.m. – 4:00 p.m.Short Talk Chosen from Submitted Abstracts
4:00 p.m. – 4:10 p.m.Discussion
4:10 p.m. – 4:25 p.m.Short Talk Chosen from Submitted Abstracts
4:25 p.m. – 4:35 p.m.Discussion
5:30 p.m. – 7:30 p.m.Salmon Bake Dinner

Jim and Diane Baker Home

(Weather permitting)

Shuttle departs at 5:15 p.m. and returns 7:30 p.m.

Monday Oct 23
6 a.m. – 8 a.m.Breakfast and depart
8:30 a.m.Bus departs for PDX Airport
~11:30 a.m.Bus arrives at PDX Airport

 

Sponsor Acknowledgement

The Montagna Symposium on the Biology of Skin is made possible due to our generous sponsors:

Sustainer Level Sponsors

 

Benefactor Level Sponsors

Janssen

 

Patron Level Sponsors

 

Associate Level Sponsors

 

Knight Cancer Institute
CTA Pathology
Biology of Skin Foundation
Orlucent

 

Travel Awards made possible thanks to:

  • Society for Investigative Dermatology (Eugene Farber Awards)
  • Japanese Society for Investigative Dermatology
  • Korean Society for Investigative Dermatology