Program subject to change

2023:

Visualizing the Future of Skin Biology and Dermatology

The 70th anniversary Montagna Symposium on the Biology of Skin, chaired by Dr. Dennis Roop, will take a broad look into the future of skin biology and Dermatology and include sessions on Skin Cancers, Tissue Repair and Fibrosis, Skin Inflammation and Keratinocyte – Immune Cell Cross-talk, and Emerging Therapeutic Approaches. Joe Gray, Ph.D. (OHSU) will provide the keynote speech.

Program Chair
Dennis Roop, Ph.D.

Co-Organizers
Stuart Yuspa, M.D.
Thomas Krieg, M.D., Ph.D.
Sabine Werner, Ph.D.

Session 1: Skin Cancer, Chair: Stuart Yuspa, MD (NIH)
Session 2: Tissue Repair and Fibrosis, Chair: Thomas Krieg, MD, PhD (Cologne)
Session 3: Keratinocyte – Immune Cell Cross-talk in Skin Inflammation, Chair: Sabine Werner, PhD (ETH Zurich)
Session 4: Emerging Therapeutic Approaches, Chair Dennis Roop (Colorado)

2022 Program:

Thursday, Oct 20
2:00 p.m. – 4:00 p.m.	Shuttle Bus from PDX Leaves (reservation required)
4:00 p.m. -5:45 p.m.	Arrival and Check-in
5:45 p.m. – 6:45 p.m.	Welcome Reception (Heavy appetizers served. Dinner on own)
6:45p.m.- 7:15p.m	Introductory Comments Sancy Leachman, M.D., Ph.D. (Oregon Health & Science University) Robert L. Modlin, M.D. (University of California, Los Angeles)
7:15 p.m. – 8:15 p.m.	Keynote: Yasmine Belkaid, Ph.D. (National Institutes of Health) “Multikingdom control of skin immunity”

Friday, Oct 21
7:00 a.m. – 7:55 a.m.	Breakfast
7:55 a.m. – 8:05 a.m.	Introductory Remarks Sancy Leachman, M.D., Ph.D. (Oregon Health & Science University) Robert L. Modlin, M.D. (University of California, Los Angeles)
8:05 a.m. – 8:15 a.m.	Session 1: Microbial immunity and pathogenesis Session Moderator: Daniel Kaplan, M.D., Ph.D.
8:15 a.m. – 8:45 a.m.	Robert L. Modlin, M.D. (University of Los Angeles, California) “Linking immune responses and lipid metabolism to antimicrobial responses in skin”
8:45 a.m. – 8:55 a.m.	Discussion
8:55 a.m. – 9:25 a.m.	Daniel Kaplan, M.D., Ph.D. (University of Pittsburgh) “Cutaneous neurons modulating immune responses”
9:25 a.m. – 9:35 a.m.	Discussion
9:35 a.m. – 9:50 a.m.	Roberto Ricardo-Gonzalez, M.D., Ph.D. (University of California, San Francisco) “Innate type 2 immunity controls hair follicle commensalism by Demodex mites”
9:50 a.m. – 10:10 a.m.	Coffee Break
10:10 a.m. – 10:40 a.m.	Isaac Chiu, Ph.D. (Harvard University) “Microbes and nerves: S. aureus driven itch and skin damage”
10:40 a.m. – 10:50 a.m.	Discussion
10:50 a.m. – 11:20 a.m.	Annemieke de Jong, Ph.D. (Columbia University) “Recognition of bacterial lipids by human T cells through CD1a”
11:20 a.m. – 11:30 a.m.	Discussion
11:30 a.m. – 11:45 a.m.	Nathan Archer, Ph.D. (Johns Hopkins School of Medicine) “Neutrophil-intrinsic TNF receptor signaling orchestrates host defense against Staphylococcus aureus”
11:45 a.m. – 12 noon	George Agak, MSc, Ph.D. (University of Los Angeles, California) “To trap a pathogen: TH17 cell-mediated extracellular traps release and their role in host defense in acne”
12 noon – 1:15 p.m.	Lunch & Funding Forum
12:30 p.m. – 1 p.m.	Ricardo Cibotti, Ph.D. (NIAMS / NIH) Funding Forum: Emerging challenges and opportunities
1:15 p.m. – 1:25 p.m.	Session 2: The microbiome in infection, autoimmunity and cancer Session Moderator: Robert Modlin, M.D.
1:25 p.m. – 1:55 p.m.	Julie Segre, Ph.D. (National Institutes of Health) “Human Skin Microbiome: Finding Friends and Foes”
1:55 p.m. – 2:05 p.m.	Discussion
2:05 p.m. – 2:35 p.m.	Tiffany Scharschmidt, M.D. (University of California, San Francisco) “Early life immune-microbe crosstalk in skin”
2:35 p.m. – 2:45 p.m.	Discussion
2:45 p.m. – 3:00 p.m.	Erin Chen, M.D., Ph.D. (Stanford) “Defining the functional properties of commensal-induced T cells by redirecting them against a non-native antigen”
3:00 p.m. – 3:15 p.m.	Lynn Petukhova, Ph.D. (Columbia University) “Monogenic mutations implicate STAT1 in hidradenitis suppurativa pathogenesis.”
3:15 p.m. – 3:35 p.m.	Coffee Break
3:35 p.m. – 4:05 p.m.	Heidi Kong, M.D., M.H.Sc. (NIAMS / NIH) “The Microbiome in Human Skin Disease”
4:05 p.m. – 4:15 p.m.	Discussion
4:15 p.m. – 4:45 p.m.	Keisuke (Chris) Nagao, M.D., Ph.D. (NIAMS / NIH) “Intersection of tissue, immunity and the microbiota in skin”
4:45 p.m. – 4:55 p.m.	Discussion
5:00 p.m.	Awards Presentation · Society of Investigative Dermatology Eugene M. Farber Travel Awards for Young Investigators · Japanese Society for Investigative Dermatology Travel Award · Korean Society for Investigative Dermatology Travel Award · Director’s Award for Diversity
5:15 p.m. – 7:00 p.m.	Poster Reception (Heavy appetizers served)
7:00 p.m. – 8:00 p.m.	Wine tasting in Long house lobby (optional) (Light snacks served)

Saturday, Oct 22
7:00 a.m. – 7:55 a.m.	Breakfast
8:00 a.m. – 8:05 a.m.	Announcements
8:05 a.m. – 8:15 a.m.	Session 3: Autoimmunity Session Moderator: John O’Shea, M.D.
8:15 a.m. – 8:45 a.m.	John O’Shea, M.D. (NIAMS /NIH) “Lymphocytes and Superenhancers”
8:45 a.m. – 8:55 a.m.	Discussion
8:55 a.m. – 9:25 a.m.	Teri Greiling, M.D., Ph.D. (Oregon Health & Science University) “Lupus and the microbiota”
9:25 a.m. – 9:35 a.m.	Discussion
9:35 a.m. – 10:05 a.m.	Raymond Cho, M.D., Ph.D. (University of California, San Francisco) “Single-cell interrogation of inflammatory skin disease”
10:05 a.m. – 10:15 a.m.	Discussion
10:15 a.m. – 10:35 a.m.	Break
10:35 a.m. – 11:05 a.m.	Michel Gilliet, M.D. (Lausanne University Hospital, Switzerland) “Targeting immune pathways in inflammatory diseases”
11:05 a.m. – 11:15 a.m.	Discussion
11:15 a.m. – 11:30 a.m.	Sarah Whitley, M.D., Ph.D. (University of Pittsburgh) “Local IL-23 is required for proliferation and retention of skin-resident memory Th17 cells”
11:30 a.m. – 11:45 a.m.	Ian Boothby, Ph.D. (University of California, San Francisco) “Early Life Inflammation Primes a Th2-Fibroblast Niche in Skin”
11:45 a.m.	Lunch on own
1:30 p.m.	FREE TIME / GOLF / CASCADE HIKE
12:00pm – 2:00pm	Melanoma Prevention Working Group (Optional, Non-members are welcome, Long House Auditorium)
4:45 p.m. – 5:50pm	Mentorship Mixer
6 p.m. – 7:15 p.m.	Dinner
7:15 p.m. – 8:15 p.m.	Keynote: Laura Mackay, Ph.D. (The University of Melbourne, Australia) “Local Immune Protection by CD8+ Tissue-Resident Memory T Cells”

Sunday, Oct 23
7:00 a.m. – 7:55 a.m.	Breakfast
8:00 a.m. – 8:05 a.m.	Announcements
8:05 a.m. – 8:15 a.m.	Session 4: Tumor immunology and prevention Session Moderator: Niroshana Anandasabapathy, M.D., Ph.D.
8:15 a.m. – 8:45 a.m.	Niroshana Anandasabapathy, M.D., Ph.D. (Weill Cornell Medicine) “Cancer immune surveillance in tissues: where it begins and ends”
8:45 a.m. – 8:55 a.m.	Discussion
8:55 a.m. – 9:25 a.m.	Jean Tang, M.D., Ph.D. (Stanford) “Small molecule and gene therapy approaches for BCC and SCC prevention in rare diseases”
9:25 a.m. – 9:35 a.m.	Discussion
9:35 a.m. – 10:05 a.m.	Shruti Naik, Ph.D. (New York University School of Medicine) “Immune-epithelial crosstalk in skin inflammation and repair”
10:05 a.m. – 10:15 a.m.	Discussion
10:15 a.m. – 11:00 a.m.	Break
11:00 a.m. – 11:15 a.m.	Liang Deng, M.D., Ph.D. (Memorial Sloan Kettering Cancer Center) “Reprogramming tumor microenvironment by a second-generation recombinant modified vaccinia virus Ankara”
11:15 a.m. – 11:30 a.m.	Zach Garrison (Oregon Health & Science University) “A novel MIF modulator as a melanoma therapeutic”
11:30 a.m. – 11:45 a.m.	Kazumasa Oya, Ph.D. (University of Tsukuba, Japan) “Eribulin mesylate exerts antitumor effects via CD103″
11:45 a.m. – 12:00 p.m.	Sergei Koralov, Ph.D. (New York University School of Medicine) “Clonal evolution and microbial triggers in Cutaneous T Cell Lymphoma pathogenesis”
12:00 p.m. – 1:00 p.m.	Lunch
1:00 p.m. – 1:10 p.m.	Session 5: Immune and biologic intervention Session Moderator: Richard Gallo, M.D., Ph.D.
1:10 p.m. – 1:40 p.m.	Richard Gallo, M.D., Ph.D. (University of California, San Diego) “Pathogen Response in the Skin”
1:40 p.m. – 1:50 p.m.	Discussion
1:50 p.m. – 2:20 p.m.	Eynav Klechevsky, Ph.D. (Washington University in St. Louis) “Regulation and dysregulation of Immune Responses by human skin dendritic cell subsets”
2:20 p.m. – 2:30 p.m.	Discussion
2:30 p.m. – 3:00 p.m.	Philip Scumpia, M.D., Ph.D. (University of Los Angeles, California) “Refining immunomodulatory biomaterials for skin applications”
3:00 p.m. – 3:10 p.m.	Discussion
3:10 p.m. – 3:30 p.m.	Break
3:30 p.m. – 4:00 p.m.	Brian Kim, M.D. (Mount Sinai) “Neuroimmune Regulation of Itch”
4:00 p.m. – 4:10 p.m.	Discussion
5:30 p.m. – 7:30 p.m.	Salmon Bake Dinner Jim and Diane Baker Home (Weather permitting) Shuttle departs at 5:15 p.m. and returns 7:30 p.m.